Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Mylius, V.; Baars, J.H.; Witt, K.; Benninger, D.; de Andrade, D.C.; Kägi, G.; Bally, J.F.; Brugger, F.

doi:10.1002/mds.29666

Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Details

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State: Public
Version: Final published version
License: CC BY-NC-ND 4.0

Serval ID

serval:BIB_F903D75F5C71

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Journal

Movement disorders

Author(s)

Mylius V., Baars J.H., Witt K., Benninger D., de Andrade D.C., Kägi G., Bally J.F., Brugger F.

ISSN

1531-8257 (Electronic)

ISSN-L

0885-3185

Publication state

Published

Issued date

02/2024

Peer-reviewed

Oui

Volume

Number

Pages

447-449

Language

english

Notes

Publication types: Letter
Publication Status: ppublish

Abstract

Dopamine exerts antinociceptive effects on pain in PD at cortical and spinal levels, whereas only cortical effects have been described for DBS, so far. By assessing the nociceptive flexion reflex (NFR) threshold at medication on, and DBS ON and OFF in two patients, we showed that DBS additionally decreases spinal nociception.

Keywords

Humans, Pain Threshold/physiology, Nociception/physiology, Deep Brain Stimulation, Parkinson Disease/complications, Parkinson Disease/therapy, Pain Measurement, Pain/etiology

URN

urn:nbn:ch:serval-BIB_F903D75F5C712

OAI-PMH

oai:serval.unil.ch:BIB_F903D75F5C71

DOI

10.1002/mds.29666

Pubmed

38071401

Web of science

001118749900001

Open Access

Yes