Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.
Details
State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_F903D75F5C71
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.
Journal
Movement disorders
ISSN
1531-8257 (Electronic)
ISSN-L
0885-3185
Publication state
Published
Issued date
02/2024
Peer-reviewed
Oui
Volume
39
Number
2
Pages
447-449
Language
english
Notes
Publication types: Letter
Publication Status: ppublish
Publication Status: ppublish
Abstract
Dopamine exerts antinociceptive effects on pain in PD at cortical and spinal levels, whereas only cortical effects have been described for DBS, so far. By assessing the nociceptive flexion reflex (NFR) threshold at medication on, and DBS ON and OFF in two patients, we showed that DBS additionally decreases spinal nociception.
Keywords
Humans, Pain Threshold/physiology, Nociception/physiology, Deep Brain Stimulation, Parkinson Disease/complications, Parkinson Disease/therapy, Pain Measurement, Pain/etiology
Pubmed
Web of science
Open Access
Yes
Create date
15/12/2023 10:20
Last modification date
12/03/2024 8:07