Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Mylius, V.; Baars, J.H.; Witt, K.; Benninger, D.; de Andrade, D.C.; Kägi, G.; Bally, J.F.; Brugger, F.

doi:10.1002/mds.29666

Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Détails

Télécharger: 38071401.pdf (195.24 [Ko])
Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0

ID Serval

serval:BIB_F903D75F5C71

Type

Article: article d'un périodique ou d'un magazine.

Collection

Publications

Institution

UNIL/CHUV

Titre

Deep Brain Stimulation Improves Parkinson's Disease-Associated Pain by Decreasing Spinal Nociception.

Périodique

Movement disorders

Auteur⸱e⸱s

Mylius V., Baars J.H., Witt K., Benninger D., de Andrade D.C., Kägi G., Bally J.F., Brugger F.

ISSN

1531-8257 (Electronic)

ISSN-L

0885-3185

Statut éditorial

Publié

Date de publication

02/2024

Peer-reviewed

Oui

Volume

Numéro

Pages

447-449

Langue

anglais

Notes

Publication types: Letter
Publication Status: ppublish

Résumé

Dopamine exerts antinociceptive effects on pain in PD at cortical and spinal levels, whereas only cortical effects have been described for DBS, so far. By assessing the nociceptive flexion reflex (NFR) threshold at medication on, and DBS ON and OFF in two patients, we showed that DBS additionally decreases spinal nociception.

Mots-clé

Humans, Pain Threshold/physiology, Nociception/physiology, Deep Brain Stimulation, Parkinson Disease/complications, Parkinson Disease/therapy, Pain Measurement, Pain/etiology

URN

urn:nbn:ch:serval-BIB_F903D75F5C712

OAI-PMH

oai:serval.unil.ch:BIB_F903D75F5C71

DOI

10.1002/mds.29666

Pubmed

38071401

Web of science

001118749900001

Open Access

Oui