Calcium pyrophosphate deposition disease: a frequent finding in patients with long-standing erosive gout.
Details
Serval ID
serval:BIB_F37201F54E3A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Calcium pyrophosphate deposition disease: a frequent finding in patients with long-standing erosive gout.
Journal
Scandinavian journal of rheumatology
ISSN
1502-7732 (Electronic)
ISSN-L
0300-9742
Publication state
Published
Issued date
03/2018
Peer-reviewed
Oui
Volume
47
Number
2
Pages
127-130
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To characterize patients with both monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in their synovial fluid (SF).
Forty-nine gout patients with acute arthritis were included. Those patients with MSU crystals only in their SF were compared to those patients with both MSU and CPP crystals in their SF.
A total of 36 out of 49 patients (73.5%) had only MSU crystals, whereas 13 out of 49 (26.5%) had both MSU and CPP crystals in their SF. Co-deposition of CPP crystals was associated with long-standing gout disease (p = 0.022), kidney dysfunction (p = 0.024), and erosive arthritis (p = 0.049), but not with age.
Long-standing gout may be a risk factor for CPP deposition disease, and the frequency of CPP co-deposition may be higher than expected.
Forty-nine gout patients with acute arthritis were included. Those patients with MSU crystals only in their SF were compared to those patients with both MSU and CPP crystals in their SF.
A total of 36 out of 49 patients (73.5%) had only MSU crystals, whereas 13 out of 49 (26.5%) had both MSU and CPP crystals in their SF. Co-deposition of CPP crystals was associated with long-standing gout disease (p = 0.022), kidney dysfunction (p = 0.024), and erosive arthritis (p = 0.049), but not with age.
Long-standing gout may be a risk factor for CPP deposition disease, and the frequency of CPP co-deposition may be higher than expected.
Keywords
Aged, Aged, 80 and over, Calcium Pyrophosphate/metabolism, Chondrocalcinosis/epidemiology, Female, Gout/metabolism, Gout/pathology, Humans, Male, Middle Aged, Prevalence, Prospective Studies, Synovial Fluid/chemistry, Uric Acid/metabolism
Pubmed
Web of science
Create date
07/12/2017 13:20
Last modification date
23/10/2019 6:13
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