Calcium pyrophosphate deposition disease: a frequent finding in patients with long-standing erosive gout.
Détails
ID Serval
serval:BIB_F37201F54E3A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Calcium pyrophosphate deposition disease: a frequent finding in patients with long-standing erosive gout.
Périodique
Scandinavian journal of rheumatology
ISSN
1502-7732 (Electronic)
ISSN-L
0300-9742
Statut éditorial
Publié
Date de publication
03/2018
Peer-reviewed
Oui
Volume
47
Numéro
2
Pages
127-130
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
To characterize patients with both monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in their synovial fluid (SF).
Forty-nine gout patients with acute arthritis were included. Those patients with MSU crystals only in their SF were compared to those patients with both MSU and CPP crystals in their SF.
A total of 36 out of 49 patients (73.5%) had only MSU crystals, whereas 13 out of 49 (26.5%) had both MSU and CPP crystals in their SF. Co-deposition of CPP crystals was associated with long-standing gout disease (p = 0.022), kidney dysfunction (p = 0.024), and erosive arthritis (p = 0.049), but not with age.
Long-standing gout may be a risk factor for CPP deposition disease, and the frequency of CPP co-deposition may be higher than expected.
Forty-nine gout patients with acute arthritis were included. Those patients with MSU crystals only in their SF were compared to those patients with both MSU and CPP crystals in their SF.
A total of 36 out of 49 patients (73.5%) had only MSU crystals, whereas 13 out of 49 (26.5%) had both MSU and CPP crystals in their SF. Co-deposition of CPP crystals was associated with long-standing gout disease (p = 0.022), kidney dysfunction (p = 0.024), and erosive arthritis (p = 0.049), but not with age.
Long-standing gout may be a risk factor for CPP deposition disease, and the frequency of CPP co-deposition may be higher than expected.
Mots-clé
Aged, Aged, 80 and over, Calcium Pyrophosphate/metabolism, Chondrocalcinosis/epidemiology, Female, Gout/metabolism, Gout/pathology, Humans, Male, Middle Aged, Prevalence, Prospective Studies, Synovial Fluid/chemistry, Uric Acid/metabolism
Pubmed
Web of science
Création de la notice
07/12/2017 13:20
Dernière modification de la notice
23/10/2019 6:13
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