Phosphorylation of CARMA1: the link(er) to NF-kappaB activation.
Details
Serval ID
serval:BIB_EE535738DC3E
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Institution
Title
Phosphorylation of CARMA1: the link(er) to NF-kappaB activation.
Journal
Immunity
ISSN
1074-7613[print], 1074-7613[linking]
Publication state
Published
Issued date
2005
Volume
23
Number
6
Pages
551-553
Language
english
Abstract
Antigen receptor-induced NF-kappaB activation depends on receptor-proximal and -distal signaling events. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-kappaB.
Keywords
Animals, Apoptosis Regulatory Proteins/metabolism, CARD Signaling Adaptor Proteins, Guanylate Kinase/metabolism, Immunity, Cellular/physiology, NF-kappa B/metabolism, Phosphorylation, Protein Kinase C/metabolism, Receptors, Antigen/metabolism, Signal Transduction/immunology, Transcriptional Activation/immunology
Pubmed
Web of science
Open Access
Yes
Create date
24/01/2008 15:11
Last modification date
20/08/2019 16:15
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