Phosphorylation of CARMA1: the link(er) to NF-kappaB activation.
Détails
ID Serval
serval:BIB_EE535738DC3E
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Lettre (letter): communication adressée à l'éditeur.
Collection
Publications
Institution
Titre
Phosphorylation of CARMA1: the link(er) to NF-kappaB activation.
Périodique
Immunity
ISSN
1074-7613[print], 1074-7613[linking]
Statut éditorial
Publié
Date de publication
2005
Volume
23
Numéro
6
Pages
551-553
Langue
anglais
Résumé
Antigen receptor-induced NF-kappaB activation depends on receptor-proximal and -distal signaling events. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-kappaB.
Mots-clé
Animals, Apoptosis Regulatory Proteins/metabolism, CARD Signaling Adaptor Proteins, Guanylate Kinase/metabolism, Immunity, Cellular/physiology, NF-kappa B/metabolism, Phosphorylation, Protein Kinase C/metabolism, Receptors, Antigen/metabolism, Signal Transduction/immunology, Transcriptional Activation/immunology
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 16:11
Dernière modification de la notice
20/08/2019 17:15
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