Genetics of drug resistance in tuberculosis

Details

Serval ID
serval:BIB_EB973C7B473D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Genetics of drug resistance in tuberculosis
Journal
Clinics in Chest Medicine
Author(s)
Telenti  A.
ISSN
0272-5231 (Print)
Publication state
Published
Issued date
03/1997
Volume
18
Number
1
Pages
55-64
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Mar
Abstract
In the last few years, there has been considerable progress in our understanding of the mechanisms of action and resistance to antimycobacterials. To date, there is information about 11 genes involved in resistance in M. tuberculosis. This has prompted the development of novel tests for the rapid identification of resistant strains, and has provided invaluable insight into unique mycobacterial structures, which are important targets for the development of new inhibitory compounds.
Keywords
Antitubercular Agents/pharmacology Drug Resistance, Microbial/*genetics Drug Resistance, Multiple Humans Mutation Mycobacterium tuberculosis/drug effects/*genetics/pathogenicity Polymerase Chain Reaction/methods Tuberculosis/diagnosis Virulence
Pubmed
Web of science
Create date
25/01/2008 14:46
Last modification date
20/08/2019 16:13
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