Genetics of drug resistance in tuberculosis
Détails
ID Serval
serval:BIB_EB973C7B473D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Genetics of drug resistance in tuberculosis
Périodique
Clinics in Chest Medicine
ISSN
0272-5231 (Print)
Statut éditorial
Publié
Date de publication
03/1997
Volume
18
Numéro
1
Pages
55-64
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Mar
Research Support, Non-U.S. Gov't
Review --- Old month value: Mar
Résumé
In the last few years, there has been considerable progress in our understanding of the mechanisms of action and resistance to antimycobacterials. To date, there is information about 11 genes involved in resistance in M. tuberculosis. This has prompted the development of novel tests for the rapid identification of resistant strains, and has provided invaluable insight into unique mycobacterial structures, which are important targets for the development of new inhibitory compounds.
Mots-clé
Antitubercular Agents/pharmacology
Drug Resistance, Microbial/*genetics
Drug Resistance, Multiple
Humans
Mutation
Mycobacterium tuberculosis/drug effects/*genetics/pathogenicity
Polymerase Chain Reaction/methods
Tuberculosis/diagnosis
Virulence
Pubmed
Web of science
Création de la notice
25/01/2008 14:46
Dernière modification de la notice
20/08/2019 16:13