Genetics of drug resistance in tuberculosis
Details
Serval ID
serval:BIB_EB973C7B473D
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Genetics of drug resistance in tuberculosis
Journal
Clinics in Chest Medicine
ISSN
0272-5231 (Print)
Publication state
Published
Issued date
03/1997
Volume
18
Number
1
Pages
55-64
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Mar
Research Support, Non-U.S. Gov't
Review --- Old month value: Mar
Abstract
In the last few years, there has been considerable progress in our understanding of the mechanisms of action and resistance to antimycobacterials. To date, there is information about 11 genes involved in resistance in M. tuberculosis. This has prompted the development of novel tests for the rapid identification of resistant strains, and has provided invaluable insight into unique mycobacterial structures, which are important targets for the development of new inhibitory compounds.
Keywords
Antitubercular Agents/pharmacology
Drug Resistance, Microbial/*genetics
Drug Resistance, Multiple
Humans
Mutation
Mycobacterium tuberculosis/drug effects/*genetics/pathogenicity
Polymerase Chain Reaction/methods
Tuberculosis/diagnosis
Virulence
Pubmed
Web of science
Create date
25/01/2008 14:46
Last modification date
20/08/2019 16:13
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