A fast automated screening method for the detection of blood transfusion in sports.

Details

Serval ID
serval:BIB_EB7D47262943
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A fast automated screening method for the detection of blood transfusion in sports.
Journal
Drug Testing and Analysis
Author(s)
Leuenberger N., Ansermet C., Pottgiesser T., Baume N., Robinson N., Saugy M., Schumacher Y.O.
ISSN
1942-7611 (Electronic)
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
6
Number
11-12
Pages
1141-1143
Language
english
Notes
Publication types: Journal Article
Abstract
Currently, there is no simple direct screening method for the misuse of blood transfusions in sports. In this study, we investigated whether the measurement of iron in EDTA-plasma can serve as biomarker for such purpose. Our results revealed an increase of the plasma iron level up to 25-fold 6 h after blood re-infusion. The variable remained elevated 10-fold one day after the procedure. A specificity of 100% and a sensitivity of 93% were obtained with a proposed threshold at 45 µg/dL of plasma iron. Therefore, our test could be used as a simple, cost effective biomarker for the screening for blood transfusion misuse in sports. Copyright © 2014 John Wiley & Sons, Ltd.
Keywords
anti-doping, blood transfusion, iron, doping
Pubmed
Web of science
Create date
26/05/2014 7:47
Last modification date
20/08/2019 16:13
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