A fast automated screening method for the detection of blood transfusion in sports.

Détails

ID Serval
serval:BIB_EB7D47262943
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
A fast automated screening method for the detection of blood transfusion in sports.
Périodique
Drug Testing and Analysis
Auteur⸱e⸱s
Leuenberger N., Ansermet C., Pottgiesser T., Baume N., Robinson N., Saugy M., Schumacher Y.O.
ISSN
1942-7611 (Electronic)
Statut éditorial
Publié
Date de publication
2014
Peer-reviewed
Oui
Volume
6
Numéro
11-12
Pages
1141-1143
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Currently, there is no simple direct screening method for the misuse of blood transfusions in sports. In this study, we investigated whether the measurement of iron in EDTA-plasma can serve as biomarker for such purpose. Our results revealed an increase of the plasma iron level up to 25-fold 6 h after blood re-infusion. The variable remained elevated 10-fold one day after the procedure. A specificity of 100% and a sensitivity of 93% were obtained with a proposed threshold at 45 µg/dL of plasma iron. Therefore, our test could be used as a simple, cost effective biomarker for the screening for blood transfusion misuse in sports. Copyright © 2014 John Wiley & Sons, Ltd.
Mots-clé
anti-doping, blood transfusion, iron, doping
Pubmed
Web of science
Création de la notice
26/05/2014 8:47
Dernière modification de la notice
20/08/2019 17:13
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