Cefaclor versus amoxicillin in the treatment of bacterial pneumonia: a comparative double-blind study
Details
Serval ID
serval:BIB_E330F4766C43
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cefaclor versus amoxicillin in the treatment of bacterial pneumonia: a comparative double-blind study
Journal
European Journal of Clinical Microbiology
ISSN
0722-2211 (Print)
Publication state
Published
Issued date
02/1983
Volume
2
Number
1
Pages
11-6
Notes
Clinical Trial
Comparative Study
Journal Article --- Old month value: Feb
Comparative Study
Journal Article --- Old month value: Feb
Abstract
A randomized double-blind controlled trial was carried out to compare the effectiveness and side-effects of cefaclor with those of amoxicillin in the treatment of 34 patients hospitalized because of acute bacterial pulmonary infection. Cefaclor and amoxicillin were given three times daily before meals in a dosage of 500 and 750 mg respectively for seven days. The cure rate was 94% in the group of patients treated with cefaclor and 89% in the group treated with amoxicillin. According to all the parameters used to assess outcome, no significant difference was found between the two antibiotics tested. In this study, cefaclor and amoxicillin appeared to be of equal value in the treatment of bacterial pneumonia or bronchopneumonia.
Keywords
Adult
Amoxicillin/*therapeutic use
Bacteria/drug effects
Cefaclor/*therapeutic use
Cephalexin/*analogs & derivatives
Clinical Trials
Double-Blind Method
Humans
Microbial Sensitivity Tests
Pneumonia/*drug therapy/microbiology
Pubmed
Web of science
Create date
25/01/2008 10:49
Last modification date
20/08/2019 17:07