Cefaclor versus amoxicillin in the treatment of bacterial pneumonia: a comparative double-blind study

Détails

ID Serval
serval:BIB_E330F4766C43
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Cefaclor versus amoxicillin in the treatment of bacterial pneumonia: a comparative double-blind study
Périodique
European Journal of Clinical Microbiology
Auteur(s)
Leuenberger  P., Vrantchev  S.
ISSN
0722-2211 (Print)
Statut éditorial
Publié
Date de publication
02/1983
Volume
2
Numéro
1
Pages
11-6
Notes
Clinical Trial
Comparative Study
Journal Article --- Old month value: Feb
Résumé
A randomized double-blind controlled trial was carried out to compare the effectiveness and side-effects of cefaclor with those of amoxicillin in the treatment of 34 patients hospitalized because of acute bacterial pulmonary infection. Cefaclor and amoxicillin were given three times daily before meals in a dosage of 500 and 750 mg respectively for seven days. The cure rate was 94% in the group of patients treated with cefaclor and 89% in the group treated with amoxicillin. According to all the parameters used to assess outcome, no significant difference was found between the two antibiotics tested. In this study, cefaclor and amoxicillin appeared to be of equal value in the treatment of bacterial pneumonia or bronchopneumonia.
Mots-clé
Adult Amoxicillin/*therapeutic use Bacteria/drug effects Cefaclor/*therapeutic use Cephalexin/*analogs & derivatives Clinical Trials Double-Blind Method Humans Microbial Sensitivity Tests Pneumonia/*drug therapy/microbiology
Pubmed
Web of science
Création de la notice
25/01/2008 9:49
Dernière modification de la notice
20/08/2019 16:07
Données d'usage