Molekulare Virologie der Hepatitis C. [Molecular virology of hepatitis C]
Details
Serval ID
serval:BIB_DD36226F7076
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Molekulare Virologie der Hepatitis C. [Molecular virology of hepatitis C]
Journal
Schweizerische Rundschau fur Medizin Praxis
ISSN
1013-2058 (Print)
Publication state
Published
Issued date
12/2002
Volume
91
Number
51-52
Pages
2247-53
Notes
Comparative Study
English Abstract
Journal Article
Review --- Old month value: Dec 18
English Abstract
Journal Article
Review --- Old month value: Dec 18
Abstract
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Here, we will briefly review current concepts of the molecular virology of hepatitis C. In vitro and in vivo models of HCV replication will be discussed in this context. Finally, novel antiviral strategies will be outlined that result from an improved understanding of the viral life cycle.
Keywords
Animals
Antiviral Agents/therapeutic use
Cells, Cultured
Disease Models, Animal
Enzyme Inhibitors/therapeutic use
Forecasting
Gene Therapy
Genes, Viral
Hepacivirus/enzymology/*genetics/*physiology
Hepatitis C/complications/drug therapy/*therapy/*virology
Hepatocytes/virology
Humans
Mice
Mice, Transgenic
Pan troglodytes
Polyproteins/genetics/metabolism
Protease Inhibitors/therapeutic use
Protein Biosynthesis
RNA, Viral/genetics
Replicon/genetics
Transcription, Genetic
Tumor Cells, Cultured
Tupaia
Viral Proteins/genetics/metabolism
Virus Replication
Pubmed
Create date
25/01/2008 17:05
Last modification date
20/08/2019 17:01
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