Molekulare Virologie der Hepatitis C. [Molecular virology of hepatitis C]

Détails

ID Serval
serval:BIB_DD36226F7076
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Molekulare Virologie der Hepatitis C. [Molecular virology of hepatitis C]
Périodique
Schweizerische Rundschau fur Medizin Praxis
Auteur⸱e⸱s
Moradpour  D., Brass  V., Gosert  R., Wolk  B., Blum  H. E.
ISSN
1013-2058 (Print)
Statut éditorial
Publié
Date de publication
12/2002
Volume
91
Numéro
51-52
Pages
2247-53
Notes
Comparative Study
English Abstract
Journal Article
Review --- Old month value: Dec 18
Résumé
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Here, we will briefly review current concepts of the molecular virology of hepatitis C. In vitro and in vivo models of HCV replication will be discussed in this context. Finally, novel antiviral strategies will be outlined that result from an improved understanding of the viral life cycle.
Mots-clé
Animals Antiviral Agents/therapeutic use Cells, Cultured Disease Models, Animal Enzyme Inhibitors/therapeutic use Forecasting Gene Therapy Genes, Viral Hepacivirus/enzymology/*genetics/*physiology Hepatitis C/complications/drug therapy/*therapy/*virology Hepatocytes/virology Humans Mice Mice, Transgenic Pan troglodytes Polyproteins/genetics/metabolism Protease Inhibitors/therapeutic use Protein Biosynthesis RNA, Viral/genetics Replicon/genetics Transcription, Genetic Tumor Cells, Cultured Tupaia Viral Proteins/genetics/metabolism Virus Replication
Pubmed
Création de la notice
25/01/2008 17:05
Dernière modification de la notice
20/08/2019 17:01
Données d'usage