Palliation of dysphagia in metastatic oesogastric cancers: An international multidisciplinary position.

Details

Serval ID
serval:BIB_DAD4904FA6D1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Palliation of dysphagia in metastatic oesogastric cancers: An international multidisciplinary position.
Journal
European journal of cancer
Author(s)
Levy A., Wagner A.D., Chargari C., Moehler M., Verheij M., Durand-Labrunie J., Kissel M., Chirat E., Burtin P., Ducreux M., Boige V., Nilsson M., Boku N., Chau I., Deutsch E.
ISSN
1879-0852 (Electronic)
ISSN-L
0959-8049
Publication state
Published
Issued date
08/2020
Peer-reviewed
Oui
Volume
135
Pages
103-112
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Malignant dysphagia is the most common symptom in advanced oesogastric cancers patients. Relief of dysphagia allows quality of life improvement, nutritional replenishment and potentially improves prognosis. Chemotherapy alone is effective and should be prioritised in patients with metastatic disease a good performance status, and its impact on dysphagia should be determined before further interventions are planned. Regarding local treatments, the insertion of a covered self-expandable metallic stent is the most commonly used alternative, as it allows for the rapid relief of severe dysphagia. Although several randomised trials have highlighted the role of oesophageal brachytherapy, this technique is often not easily accessible. Contemporary trials are ongoing to better define the role of external radiation therapy. While awaiting these results, external radiation therapy can be considered as a second-best option for patients with a life-expectancy > 3 months. It is important to offer nutritional support and to integrate quality of life measures in the palliative management of dysphagia. This multidisciplinary international position paper aims to propose a decision-making process and highlight randomised trials for the management of malignant dysphagia in metastatic oesogastric cancer patients.
Keywords
Consensus, Quality of life, Supportive care, Upper gastrointestinal cancer
Pubmed
Web of science
Create date
06/07/2020 12:08
Last modification date
08/12/2020 6:24
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