A part of a book.
Chapter: chapter ou part
Planning sleep-related animal and translational research
Title of the book
Encyclopedia of Sleep
Address of publication
Vol. Assessment, Methodology, Training, and Policies of Sleep
With the aim of improving human health, scientists have been using an approach referred to as translational research, in which they aim to convey their laboratory discoveries into clinical applications to help prevent and cure disease. Such discoveries often arise from cellular, molecular, and physiological studies that progress to the clinical level. Most of the translational work is done using animal models that share common genes, molecular pathways, or phenotypes with humans. In this article, we discuss how translational work is carried out in various animal models and illustrate its relevance for human sleep research and sleep-related disorders.
Actigraphy, Animal model, Brain, Central nervous system, Circadian rhythms, Electroencephalography, Electromyography, Genetic, Homeostasis, Hypocretin/orexin, Narcolepsy, Neurotransmitters, Obesity, Obstructive sleep apnea, Piezoelectric system, Sleep, Sleep disorders, Translational research
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