Planning sleep-related animal and translational research

Détails

ID Serval
serval:BIB_D29EC89B3126
Type
Partie de livre
Sous-type
Chapitre: chapitre ou section
Collection
Publications
Institution
Titre
Planning sleep-related animal and translational research
Titre du livre
Encyclopedia of Sleep
Auteur(s)
Mang G.M., Franken P.
Editeur
Elsevier
Lieu d'édition
Amsterdam
ISBN
978-0-12-407175-9
Statut éditorial
Publié
Date de publication
2013
Editeur scientifique
Kushida C.A.
Volume
2
Pages
139-150
Langue
anglais
Notes
Vol. Assessment, Methodology, Training, and Policies of Sleep
Résumé
With the aim of improving human health, scientists have been using an approach referred to as translational research, in which they aim to convey their laboratory discoveries into clinical applications to help prevent and cure disease. Such discoveries often arise from cellular, molecular, and physiological studies that progress to the clinical level. Most of the translational work is done using animal models that share common genes, molecular pathways, or phenotypes with humans. In this article, we discuss how translational work is carried out in various animal models and illustrate its relevance for human sleep research and sleep-related disorders.
Mots-clé
Actigraphy, Animal model, Brain, Central nervous system, Circadian rhythms, Electroencephalography, Electromyography, Genetic, Homeostasis, Hypocretin/orexin, Narcolepsy, Neurotransmitters, Obesity, Obstructive sleep apnea, Piezoelectric system, Sleep, Sleep disorders, Translational research
Création de la notice
17/01/2013 10:00
Dernière modification de la notice
20/08/2019 15:52
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