Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
The cytoskeleton and disease
Journal of Pathology
PT - Journal Article PT - Review
Cytoskeletal research in recent years has revolutionized cell biology and biomedicine. The cytoskeleton spans the cytoplasm and interconnects the cell nucleus with the extracellular matrix, thereby forming a structural link between molecules involved in cell communication on the one hand, and gene expression on the other. Since the cytoskeleton is involved in virtually all cellular processes, abnormalities in this essential cellular component frequently result in disease. In this introduction, the basic structure of the cytoskeleton is briefly outlined. Furthermore, the disease processes in which the cytoskeleton plays a decisive role, and which are reviewed in detail in the papers in this issue, are briefly introduced. The advances in our understanding of the cytoskeleton and its function in disease will lead to new diagnostic and therapeutic applications in the foreseeable future
Actins/metabolism/Cell Nucleus/Cytoskeletal Proteins/classification/Cytoskeleton/physiology/Hematologic Diseases/etiology/Humans/Intestinal Diseases/Keratins/Liver Diseases/Lymphatic Diseases/Muscular Diseases/Neurodegenerative Diseases/Skin Diseases
Web of science
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