The cytoskeleton and disease

Détails

ID Serval
serval:BIB_BB81BBD14EED
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
The cytoskeleton and disease
Périodique
Journal of Pathology
Auteur(s)
Ramaekers  F. C., Bosman  F. T.
ISSN
0022-3417 (Print)
Statut éditorial
Publié
Date de publication
2004
Volume
204
Numéro
4
Pages
351-354
Notes
PT - Journal Article PT - Review
Résumé
Cytoskeletal research in recent years has revolutionized cell biology and biomedicine. The cytoskeleton spans the cytoplasm and interconnects the cell nucleus with the extracellular matrix, thereby forming a structural link between molecules involved in cell communication on the one hand, and gene expression on the other. Since the cytoskeleton is involved in virtually all cellular processes, abnormalities in this essential cellular component frequently result in disease. In this introduction, the basic structure of the cytoskeleton is briefly outlined. Furthermore, the disease processes in which the cytoskeleton plays a decisive role, and which are reviewed in detail in the papers in this issue, are briefly introduced. The advances in our understanding of the cytoskeleton and its function in disease will lead to new diagnostic and therapeutic applications in the foreseeable future
Mots-clé
Actins/metabolism/Cell Nucleus/Cytoskeletal Proteins/classification/Cytoskeleton/physiology/Hematologic Diseases/etiology/Humans/Intestinal Diseases/Keratins/Liver Diseases/Lymphatic Diseases/Muscular Diseases/Neurodegenerative Diseases/Skin Diseases
Pubmed
Web of science
Open Access
Oui
Création de la notice
29/01/2008 18:36
Dernière modification de la notice
20/08/2019 15:29
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