Prise en charge chirurgicale des tumeurs stromales gastro-intestinales d’origine gastrique [Surgical management of gastrointestinal stromal tumors of gastric origin]

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UNIL restricted access
State: Public
Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_B99345B4AE07
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Prise en charge chirurgicale des tumeurs stromales gastro-intestinales d’origine gastrique [Surgical management of gastrointestinal stromal tumors of gastric origin]
Journal
Revue medicale suisse
Author(s)
Chappalley D., Mantziari S., Schäfer M., Teixeira Farinha H.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
12/06/2024
Peer-reviewed
Oui
Volume
20
Number
878
Pages
1158-1162
Language
french
Notes
Publication types: Journal Article ; English Abstract
Publication Status: ppublish
Abstract
Gastrointestinal Stromal Tumors (GISTs) account for 1 to 2% of gastrointestinal malignant tumors. They are characterized by overexpression of the tyrosine kinase (KIT). 60% of GISTs originate in the stomach. Managing them remains complex and varies depending on several factors such as location, size, molecular biology, type of clinical presentation, and the risks/benefits of surgical treatment. Surgery remains the only curative treatment, while tyrosine kinase inhibitors have demonstrated their efficacy as systemic treatment in the perioperative context. Risk stratification for recurrence guides the choice of adjuvant treatment, with a recommended duration of 3 years for high-risk patients.
Keywords
Gastrointestinal Stromal Tumors/surgery, Gastrointestinal Stromal Tumors/diagnosis, Humans, Stomach Neoplasms/surgery, Stomach Neoplasms/pathology, Stomach Neoplasms/diagnosis, Neoplasm Recurrence, Local
Pubmed
Create date
20/06/2024 13:17
Last modification date
21/06/2024 6:18
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