Prise en charge chirurgicale des tumeurs stromales gastro-intestinales d’origine gastrique [Surgical management of gastrointestinal stromal tumors of gastric origin]

Détails

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Etat: Public
Version: Final published version
Licence: CC BY-NC-ND 4.0
ID Serval
serval:BIB_B99345B4AE07
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Prise en charge chirurgicale des tumeurs stromales gastro-intestinales d’origine gastrique [Surgical management of gastrointestinal stromal tumors of gastric origin]
Périodique
Revue medicale suisse
Auteur⸱e⸱s
Chappalley D., Mantziari S., Schäfer M., Teixeira Farinha H.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
12/06/2024
Peer-reviewed
Oui
Volume
20
Numéro
878
Pages
1158-1162
Langue
français
Notes
Publication types: Journal Article ; English Abstract
Publication Status: ppublish
Résumé
Gastrointestinal Stromal Tumors (GISTs) account for 1 to 2% of gastrointestinal malignant tumors. They are characterized by overexpression of the tyrosine kinase (KIT). 60% of GISTs originate in the stomach. Managing them remains complex and varies depending on several factors such as location, size, molecular biology, type of clinical presentation, and the risks/benefits of surgical treatment. Surgery remains the only curative treatment, while tyrosine kinase inhibitors have demonstrated their efficacy as systemic treatment in the perioperative context. Risk stratification for recurrence guides the choice of adjuvant treatment, with a recommended duration of 3 years for high-risk patients.
Mots-clé
Gastrointestinal Stromal Tumors/surgery, Gastrointestinal Stromal Tumors/diagnosis, Humans, Stomach Neoplasms/surgery, Stomach Neoplasms/pathology, Stomach Neoplasms/diagnosis, Neoplasm Recurrence, Local
Pubmed
Création de la notice
20/06/2024 13:17
Dernière modification de la notice
21/06/2024 6:18
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