Prevalence and Factors Associated with Prosthetic Joint Infections in Patients with Staphylococcus aureus Bacteraemia: A 7-Year Retrospective Study.
Details
Request a copy Under indefinite embargo.UNIL restricted access
State: Public
Version: author
License: CC BY 4.0
Serval ID
serval:BIB_B6E9D65B4BFE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Prevalence and Factors Associated with Prosthetic Joint Infections in Patients with Staphylococcus aureus Bacteraemia: A 7-Year Retrospective Study.
Journal
Antibiotics
ISSN
2079-6382 (Print)
ISSN-L
2079-6382
Publication state
Published
Issued date
28/09/2022
Peer-reviewed
Oui
Volume
11
Number
10
Pages
1323
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
Staphylococcus aureus is the main cause of haematogenous prosthetic joint infections (PJI). We aimed to describe the prevalence and factors associated with PJI in patients with documented S. aureus bacteraemia.
Adult patients with S. aureus bacteraemia and presence of prosthetic joint hospitalized in Lausanne University Hospital during a seven-year period (2015-2021) were included.
Among 135 patients with S. aureus bacteraemia and prosthetic joints, 38 (28%) had PJI. Multivariate analysis revealed that the presence of PJI was associated with knee arthroplasty (P 0.029; aOR 3.00, 95% CI 1.12-8.05), prior arthroplasty revision (P 0.034; aOR 3.59, 95% CI 1.10-11.74), community-acquired bacteraemia (P 0.005; aOR 4.74, 95% CI 1.61-14.01) and age < 70 years (P 0.007; aOR 9.39, 95% CI 1.84-47.85).
PJI was common among patients with documented S. aureus bacteraemia. PJI was associated with characteristics of the prosthesis, such as prior arthroplasty revisions and knee prosthesis.
Adult patients with S. aureus bacteraemia and presence of prosthetic joint hospitalized in Lausanne University Hospital during a seven-year period (2015-2021) were included.
Among 135 patients with S. aureus bacteraemia and prosthetic joints, 38 (28%) had PJI. Multivariate analysis revealed that the presence of PJI was associated with knee arthroplasty (P 0.029; aOR 3.00, 95% CI 1.12-8.05), prior arthroplasty revision (P 0.034; aOR 3.59, 95% CI 1.10-11.74), community-acquired bacteraemia (P 0.005; aOR 4.74, 95% CI 1.61-14.01) and age < 70 years (P 0.007; aOR 9.39, 95% CI 1.84-47.85).
PJI was common among patients with documented S. aureus bacteraemia. PJI was associated with characteristics of the prosthesis, such as prior arthroplasty revisions and knee prosthesis.
Keywords
Staphylococcus aureus, arthroplasty, bloodstream infection, community-acquired infection, prosthetic joint infection
Pubmed
Web of science
Open Access
Yes
Create date
09/11/2022 8:32
Last modification date
25/12/2022 6:50
Usage data
