Article: article from journal or magazin.
Male-pattern baldness susceptibility locus at 20p11.
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
We conducted a genome-wide association study for androgenic alopecia in 1,125 men and identified a newly associated locus at chromosome 20p11.22, confirmed in three independent cohorts (n = 1,650; OR = 1.60, P = 1.1 x 10(-14) for rs1160312). The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)).
Alopecia, Chromosomes, Human, Pair 20, Female, Genetic Predisposition to Disease, Genome, Human, Humans, Male, Polymorphism, Single Nucleotide
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