Article: article from journal or magazin.
Processing of the polymeric immunoglobulin receptor
Biochemical Society Symposia
The transcellular transport of polymeric immunoglobulins (pIg) across mucosal epithelia is mediated by a membrane glycoprotein known as the polymeric immunoglobulin receptor (pIgR). The intracellular routing of the pIgR has been used as a model to study protein traffic. Examination of the biosynthesis and processing of the pIgR in mammary gland and liver have led to a working hypothesis for pIgR routing in the cell. These hypotheses are currently being tested in an immortalized cell line derived from rabbit mammary gland alveolar cells.
Animals Biological Transport, Active Cell Line Cell Membrane/metabolism Immunoglobulin A/*metabolism Kinetics Phosphorylation Rabbits Rats Receptors, Immunologic/*metabolism Secretory Component
Web of science
Last modification date