Processing of the polymeric immunoglobulin receptor
Détails
ID Serval
serval:BIB_A093FDFD1F40
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Processing of the polymeric immunoglobulin receptor
Périodique
Biochemical Society Symposia
ISSN
0067-8694 (Print)
Statut éditorial
Publié
Date de publication
1989
Volume
55
Pages
125-8
Notes
Journal Article
Résumé
The transcellular transport of polymeric immunoglobulins (pIg) across mucosal epithelia is mediated by a membrane glycoprotein known as the polymeric immunoglobulin receptor (pIgR). The intracellular routing of the pIgR has been used as a model to study protein traffic. Examination of the biosynthesis and processing of the pIgR in mammary gland and liver have led to a working hypothesis for pIgR routing in the cell. These hypotheses are currently being tested in an immortalized cell line derived from rabbit mammary gland alveolar cells.
Mots-clé
Animals
Biological Transport, Active
Cell Line
Cell Membrane/metabolism
Immunoglobulin A/*metabolism
Kinetics
Phosphorylation
Rabbits
Rats
Receptors, Immunologic/*metabolism
Secretory Component
Pubmed
Web of science
Création de la notice
25/01/2008 16:05
Dernière modification de la notice
20/08/2019 16:06