Long-term effect of bariatric surgery on body composition in post-menopausal women
Details
Serval ID
serval:BIB_99454EFB498C
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Institution
Title
Long-term effect of bariatric surgery on body composition in post-menopausal women
Title of the conference
Clinical Nutrition ESPEN
ISSN
2405-4577
Publication state
Published
Issued date
12/2021
Volume
46
Pages
S562
Language
english
Notes
L2015775516
2021-12-06
2021-12-06
Abstract
Rationale: Bariatric surgery (BS) induces sustained loss of body fat mass (FM) with an inevitable loss of lean mass (LM). In contrast, menopause leads to deleterious changes in body composition (BC) related to estrogen deficiency including LM loss and increases in total and visceral adipose tissue (VAT). This study aims to assess BC in post-menopausal women after RYGB (Roux-en-Y gastric bypass) and compares their profile with age and BMI matched controls. Methods: Cross-sectional case-control study of 41 post-menopausal women aged ≥50 years who underwent RYGB at least 2 yrs prior to the study. Control population consists of 41 age and BMI-matched post-menopausal women. 2/41 BS patients and 8/41 controls were on hormone replacement therapy. Both groups had a DEXA scan to evaluate BC and a blood test to assess lipids and glucose metabolism markers. Results: Mean age was 58.4[SD=6.2] vs 59.4[SD=3.2] yrs (p=0.4) and mean BMI was 29.6[SD=4.9] vs 31.1[SD=5.6] kg/m2 (p=0.2) in BS patients vs controls, respectively. RYGB was performed a median of 90 months prior to DEXA. Total weight loss was 28.5%[SD=10] and excess weight loss was 67.5%[SD=29.2]. Compared controls, BS patients showed higher LM percentage (57.7%[SD=8%] vs 52.5%[SD=5%], p=0.001) and reduced FM (39.4%[SD=8.4%] vs 45.9%[SD=5.4%] p<0.01) associated with lower VAT (750.6[SD=496] vs 1295.3[SD=688] gr, p<0.01), and android fat (44.6%[SD=7.5%] vs 48.21%[SD=4.9%]). Post-BS women showed a better lipid profile compared to controls (total cholesterol 4.8[SD=0.9] vs 5.5[SD=0.94] mmol/l, p<0.001; LDL 2.4[SD=0.8] vs 3.4[SD=0.8] mmol/l p<0.001; HDL 1.9[SD=0.4] vs 1.6[SD=0.4] mmol/l p=0.008). Glucose markers were not different. Conclusion: Post-menopausal women after RYGB have a decreased FM and VAT with a greater LM and a better lipid profile compared to controls. Weight loss after RYGB seems to sustain long-term impact on metabolic health. Disclosure of Interest: None declared.
Keywords
Nutrition and Dietetics, Endocrinology, Diabetes and Metabolism
Create date
23/12/2021 11:55
Last modification date
15/06/2024 6:04