Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers.
Details
Serval ID
serval:BIB_9045507232AF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers.
Journal
Quality of life research
Working group(s)
Swiss Paediatric Oncology Group (SPOG)
Contributor(s)
Ammann R., Scheinemann K., Ansari M., Beck Popovic M., Brazzola P., Greiner J., Grotzer M., Hengartner H., Kuehne T., Rössler J., Niggli F., Schilling F., von der Weid N.
ISSN
1573-2649 (Electronic)
ISSN-L
0962-9343
Publication state
Published
Issued date
02/2019
Peer-reviewed
Oui
Volume
28
Number
2
Pages
515-521
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
Hearing loss, a complication of cancer treatment, may reduce health-related quality of life (HRQoL), especially in childhood cancer survivors of central nervous system (CNS) tumours who often have multiple late effects. We examined the effect of hearing loss on HRQoL in young survivors of CNS and other childhood cancers.
Within the Swiss Childhood Cancer Survivor Study, we sent questionnaires about hearing loss and HRQoL (KIDSCREEN-27) to parents of survivors aged 8-15 years. We stratified the effect of hearing loss on HRQoL by cancer diagnosis, using multivariable logistic regression and adjusting for sociodemographic and clinical factors.
Hearing loss was associated with impaired physical well-being [unadjusted estimated differences - 4.6 (CI - 9.2, - 0.1); adjusted - 4.0 (CI - 7.6, - 0.3)] and peers and social support [unadjusted - 6.7 (CI - 13.0, - 0.3); adjusted - 5.0 (CI - 10.5, 0.9)] scores in survivors of CNS tumours (n = 123), but not in children diagnosed with other cancers (all p-values > 0.20, n = 577).
Clinicians should be alert to signs of reduced physical well-being and impaired relationships with peers. Especially survivors of CNS tumours may benefit most from strict audiological monitoring and timely intervention to mitigate secondary consequences of hearing loss on HRQoL.
Within the Swiss Childhood Cancer Survivor Study, we sent questionnaires about hearing loss and HRQoL (KIDSCREEN-27) to parents of survivors aged 8-15 years. We stratified the effect of hearing loss on HRQoL by cancer diagnosis, using multivariable logistic regression and adjusting for sociodemographic and clinical factors.
Hearing loss was associated with impaired physical well-being [unadjusted estimated differences - 4.6 (CI - 9.2, - 0.1); adjusted - 4.0 (CI - 7.6, - 0.3)] and peers and social support [unadjusted - 6.7 (CI - 13.0, - 0.3); adjusted - 5.0 (CI - 10.5, 0.9)] scores in survivors of CNS tumours (n = 123), but not in children diagnosed with other cancers (all p-values > 0.20, n = 577).
Clinicians should be alert to signs of reduced physical well-being and impaired relationships with peers. Especially survivors of CNS tumours may benefit most from strict audiological monitoring and timely intervention to mitigate secondary consequences of hearing loss on HRQoL.
Keywords
Cancer Survivors/psychology, Central Nervous System Neoplasms/complications, Central Nervous System Neoplasms/pathology, Child, Preschool, Female, Hearing Loss/diagnosis, Humans, Male, Quality of Life/psychology, Surveys and Questionnaires, Cancer treatment, Childhood cancer, Late effects, Ototoxicity, Swiss Childhood Cancer Registry, Swiss Childhood Cancer Survivor Study
Pubmed
Web of science
Create date
17/10/2018 9:18
Last modification date
20/08/2019 15:53
Usage data
