Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers.
Détails
ID Serval
serval:BIB_9045507232AF
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers.
Périodique
Quality of life research
Collaborateur⸱rice⸱s
Swiss Paediatric Oncology Group (SPOG)
Contributeur⸱rice⸱s
Ammann R., Scheinemann K., Ansari M., Beck Popovic M., Brazzola P., Greiner J., Grotzer M., Hengartner H., Kuehne T., Rössler J., Niggli F., Schilling F., von der Weid N.
ISSN
1573-2649 (Electronic)
ISSN-L
0962-9343
Statut éditorial
Publié
Date de publication
02/2019
Peer-reviewed
Oui
Volume
28
Numéro
2
Pages
515-521
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Hearing loss, a complication of cancer treatment, may reduce health-related quality of life (HRQoL), especially in childhood cancer survivors of central nervous system (CNS) tumours who often have multiple late effects. We examined the effect of hearing loss on HRQoL in young survivors of CNS and other childhood cancers.
Within the Swiss Childhood Cancer Survivor Study, we sent questionnaires about hearing loss and HRQoL (KIDSCREEN-27) to parents of survivors aged 8-15 years. We stratified the effect of hearing loss on HRQoL by cancer diagnosis, using multivariable logistic regression and adjusting for sociodemographic and clinical factors.
Hearing loss was associated with impaired physical well-being [unadjusted estimated differences - 4.6 (CI - 9.2, - 0.1); adjusted - 4.0 (CI - 7.6, - 0.3)] and peers and social support [unadjusted - 6.7 (CI - 13.0, - 0.3); adjusted - 5.0 (CI - 10.5, 0.9)] scores in survivors of CNS tumours (n = 123), but not in children diagnosed with other cancers (all p-values > 0.20, n = 577).
Clinicians should be alert to signs of reduced physical well-being and impaired relationships with peers. Especially survivors of CNS tumours may benefit most from strict audiological monitoring and timely intervention to mitigate secondary consequences of hearing loss on HRQoL.
Within the Swiss Childhood Cancer Survivor Study, we sent questionnaires about hearing loss and HRQoL (KIDSCREEN-27) to parents of survivors aged 8-15 years. We stratified the effect of hearing loss on HRQoL by cancer diagnosis, using multivariable logistic regression and adjusting for sociodemographic and clinical factors.
Hearing loss was associated with impaired physical well-being [unadjusted estimated differences - 4.6 (CI - 9.2, - 0.1); adjusted - 4.0 (CI - 7.6, - 0.3)] and peers and social support [unadjusted - 6.7 (CI - 13.0, - 0.3); adjusted - 5.0 (CI - 10.5, 0.9)] scores in survivors of CNS tumours (n = 123), but not in children diagnosed with other cancers (all p-values > 0.20, n = 577).
Clinicians should be alert to signs of reduced physical well-being and impaired relationships with peers. Especially survivors of CNS tumours may benefit most from strict audiological monitoring and timely intervention to mitigate secondary consequences of hearing loss on HRQoL.
Mots-clé
Cancer Survivors/psychology, Central Nervous System Neoplasms/complications, Central Nervous System Neoplasms/pathology, Child, Preschool, Female, Hearing Loss/diagnosis, Humans, Male, Quality of Life/psychology, Surveys and Questionnaires, Cancer treatment, Childhood cancer, Late effects, Ototoxicity, Swiss Childhood Cancer Registry, Swiss Childhood Cancer Survivor Study
Pubmed
Web of science
Création de la notice
17/10/2018 9:18
Dernière modification de la notice
20/08/2019 15:53
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