Article: article from journal or magazin.
Brain spectrin(240/235) and brain spectrin(240/235E): two distinct spectrin subtypes with different locations within mammalian neural cells.
Journal of Cell Biology
Adult mouse brain contains at least two distinct spectrin subtypes, both consisting of 240-kD and 235-kD subunits. Brain spectrin(240/235) is found in neuronal axons, but not dendrites, when immunohistochemistry is performed with antibody raised against brain spectrin isolated from enriched synaptic/axonal membranes. A second spectrin subtype, brain spectrin(240/235E), is exclusively recognized by red blood cell spectrin antibody. Brain spectrin(240/235E) is confined to neuronal cell bodies and dendrites, and some glial cells, but is not present in axons or presynaptic terminals.
Animals, Axons/analysis, Brain Chemistry, Dendrites/analysis, Immune Sera/analysis, Immunoenzyme Techniques, Mice, Neurons/analysis, Organ Specificity, Spectrin/immunology, Spectrin/isolation & purification, Synaptic Membranes/analysis
Web of science
Last modification date