Brain spectrin(240/235) and brain spectrin(240/235E): two distinct spectrin subtypes with different locations within mammalian neural cells.

Détails

ID Serval
serval:BIB_89C843E0045F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Brain spectrin(240/235) and brain spectrin(240/235E): two distinct spectrin subtypes with different locations within mammalian neural cells.
Périodique
Journal of Cell Biology
Auteur(s)
Riederer B.M., Zagon I.S., Goodman S.R.
ISSN
0021-9525 (Print)
ISSN-L
0021-9525
Statut éditorial
Publié
Date de publication
1986
Volume
102
Numéro
6
Pages
2088-2097
Langue
anglais
Résumé
Adult mouse brain contains at least two distinct spectrin subtypes, both consisting of 240-kD and 235-kD subunits. Brain spectrin(240/235) is found in neuronal axons, but not dendrites, when immunohistochemistry is performed with antibody raised against brain spectrin isolated from enriched synaptic/axonal membranes. A second spectrin subtype, brain spectrin(240/235E), is exclusively recognized by red blood cell spectrin antibody. Brain spectrin(240/235E) is confined to neuronal cell bodies and dendrites, and some glial cells, but is not present in axons or presynaptic terminals.
Mots-clé
Animals, Axons/analysis, Brain Chemistry, Dendrites/analysis, Immune Sera/analysis, Immunoenzyme Techniques, Mice, Neurons/analysis, Organ Specificity, Spectrin/immunology, Spectrin/isolation & purification, Synaptic Membranes/analysis
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 14:34
Dernière modification de la notice
20/08/2019 14:48
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