Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders.

Détails

Ressource 1Télécharger: BIB_8793A0F9F431.P001.pdf (1114.97 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_8793A0F9F431
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders.
Périodique
Frontiers In Cellular Neuroscience
Auteur(s)
Petrelli F., Pucci L., Bezzi P.
ISSN
1662-5102 (Electronic)
ISSN-L
1662-5102
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
10
Pages
21
Langue
anglais
Résumé
The cellular mechanism(s) underlying autism spectrum disorders (ASDs) are not fully understood although it has been shown that various genetic and environmental factors contribute to their etiology. As increasing evidence indicates that astrocytes and microglial cells play a major role in synapse maturation and function, and there is evidence of deficits in glial cell functions in ASDs, one current hypothesis is that glial dysfunctions directly contribute to their pathophysiology. The aim of this review is to summarize microglia and astrocyte functions in synapse development and their contributions to ASDs.
Pubmed
Open Access
Oui
Création de la notice
04/03/2016 21:06
Dernière modification de la notice
08/05/2019 21:30
Données d'usage