The multifaceted adult epidermal stem cell

Détails

ID Serval
serval:BIB_870EEF888039
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
The multifaceted adult epidermal stem cell
Périodique
Current Opinion in Cell Biology
Auteur(s)
Gambardella  L., Barrandon  Y.
ISSN
0955-0674 (Print)
Statut éditorial
Publié
Date de publication
12/2003
Volume
15
Numéro
6
Pages
771-7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Dec
Résumé
Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy. Recent work has pointed to the hair follicle as the main repository of multipotent stem cells in skin. Hair follicles, which are often affected in the mouse by spontaneous or man-made mutations, have become superb model systems to study the cellular and molecular factors that regulate the proliferation, migration and fate of adult stem cells.
Mots-clé
Adult Animals Cell Differentiation Cell Division Cell Lineage Cell Movement Epidermis/*cytology/metabolism Gene Therapy Humans Models, Biological Mutation Stem Cells/*cytology
Pubmed
Web of science
Création de la notice
28/01/2008 9:41
Dernière modification de la notice
03/03/2018 19:00
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