The multifaceted adult epidermal stem cell
Détails
ID Serval
serval:BIB_870EEF888039
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
The multifaceted adult epidermal stem cell
Périodique
Current Opinion in Cell Biology
ISSN
0955-0674 (Print)
Statut éditorial
Publié
Date de publication
12/2003
Volume
15
Numéro
6
Pages
771-7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Dec
Research Support, Non-U.S. Gov't
Review --- Old month value: Dec
Résumé
Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy. Recent work has pointed to the hair follicle as the main repository of multipotent stem cells in skin. Hair follicles, which are often affected in the mouse by spontaneous or man-made mutations, have become superb model systems to study the cellular and molecular factors that regulate the proliferation, migration and fate of adult stem cells.
Mots-clé
Adult
Animals
Cell Differentiation
Cell Division
Cell Lineage
Cell Movement
Epidermis/*cytology/metabolism
Gene Therapy
Humans
Models, Biological
Mutation
Stem Cells/*cytology
Pubmed
Web of science
Création de la notice
28/01/2008 9:41
Dernière modification de la notice
20/08/2019 15:46