The multifaceted adult epidermal stem cell

Details

Serval ID
serval:BIB_870EEF888039
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The multifaceted adult epidermal stem cell
Journal
Current Opinion in Cell Biology
Author(s)
Gambardella  L., Barrandon  Y.
ISSN
0955-0674 (Print)
Publication state
Published
Issued date
12/2003
Volume
15
Number
6
Pages
771-7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Dec
Abstract
Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy. Recent work has pointed to the hair follicle as the main repository of multipotent stem cells in skin. Hair follicles, which are often affected in the mouse by spontaneous or man-made mutations, have become superb model systems to study the cellular and molecular factors that regulate the proliferation, migration and fate of adult stem cells.
Keywords
Adult Animals Cell Differentiation Cell Division Cell Lineage Cell Movement Epidermis/*cytology/metabolism Gene Therapy Humans Models, Biological Mutation Stem Cells/*cytology
Pubmed
Web of science
Create date
28/01/2008 8:41
Last modification date
20/08/2019 14:46
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