Article: article from journal or magazin.
Radiotherapy in early stage Hodgkin's disease
Leukemia and Lymphoma
Journal Article Research Support, Non-U.S. Gov't --- Old month value: Apr
Ninety-nine patients with "standard risk" Stage IA-IIA Hodgkin's disease observed between January 1983 and December 1990, received radiotherapy only. The complete response rate was 98% (97/99). Twenty-one patients (21%) relapsed, 17 of whom (81%) obtained a second complete remission. The projected 9-year overall survival and disease-free survival were 95% and 78%, respectively. In this study our goals were to reduce the irradiation volumes, to decrease the number of splenectomies performed at diagnosis, and to utilize radiotherapy alone in these patients. We were able to reduce the irradiation volumes in over 50% and 80% of the patients with disease in the upper torso and subdiaphragm, respectively. Furthermore, this therapeutic approach permitted us to reduce the acute and long-term toxic effects related to splenectomy and combined modality treatment.
Adolescent Adult Cobalt Radioisotopes/*therapeutic use Female Hodgkin Disease/mortality/pathology/*radiotherapy Humans Life Tables Male Middle Aged Neoplasm Recurrence, Local Neoplasm Staging *Radioisotope Teletherapy/adverse effects Remission Induction Salvage Therapy Splenectomy Survival Rate Treatment Outcome
Web of science
Last modification date