Radiotherapy in early stage Hodgkin's disease

Détails

ID Serval
serval:BIB_858CF309C838
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Radiotherapy in early stage Hodgkin's disease
Périodique
Leukemia and Lymphoma
Auteur⸱e⸱s
Zinzani  P. L., Barbieri  E., Gherlinzoni  F., Frezza  G., Mazza  P., Pica  A., Ammendolia  I., Bendandi  M., Neri  S., Miniaci  G., Fiacchini  M., Babini  L., Tura  S.
ISSN
1042-8194 (Print)
Statut éditorial
Publié
Date de publication
04/1994
Volume
13
Numéro
3-4
Pages
285-9
Notes
Journal Article Research Support, Non-U.S. Gov't --- Old month value: Apr
Résumé
Ninety-nine patients with "standard risk" Stage IA-IIA Hodgkin's disease observed between January 1983 and December 1990, received radiotherapy only. The complete response rate was 98% (97/99). Twenty-one patients (21%) relapsed, 17 of whom (81%) obtained a second complete remission. The projected 9-year overall survival and disease-free survival were 95% and 78%, respectively. In this study our goals were to reduce the irradiation volumes, to decrease the number of splenectomies performed at diagnosis, and to utilize radiotherapy alone in these patients. We were able to reduce the irradiation volumes in over 50% and 80% of the patients with disease in the upper torso and subdiaphragm, respectively. Furthermore, this therapeutic approach permitted us to reduce the acute and long-term toxic effects related to splenectomy and combined modality treatment.
Mots-clé
Adolescent Adult Cobalt Radioisotopes/*therapeutic use Female Hodgkin Disease/mortality/pathology/*radiotherapy Humans Life Tables Male Middle Aged Neoplasm Recurrence, Local Neoplasm Staging *Radioisotope Teletherapy/adverse effects Remission Induction Salvage Therapy Splenectomy Survival Rate Treatment Outcome
Pubmed
Web of science
Création de la notice
24/01/2008 18:18
Dernière modification de la notice
20/08/2019 15:44
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