Mammalian neural stem-cell renewal: nature versus nurture

Détails

ID Serval
serval:BIB_727A94741965
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Mammalian neural stem-cell renewal: nature versus nurture
Périodique
Molecular Neurobiology
Auteur(s)
Arsenijevic  Y.
ISSN
0893-7648 (Print)
Statut éditorial
Publié
Date de publication
02/2003
Volume
27
Numéro
1
Pages
73-98
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Feb
Résumé
Recent data show that the final events of mammalian brain organogenesis may depend in part on the direct control of neural stem cell (NSC) proliferation and survival. Environmental and intrinsic factors play a role throughout development and during adulthood to regulate NSC proliferation. The NSCs acquire new competences throughout development, including adulthood, and this change in competence is region-specific. The factors controlling NSC survival, undifferentiated state, proliferation, and cell-cycle number are beginning to be identified, but the links between them remain unclear. However, current knowledge should help to formulate an understanding of how a stem cell can generate a new stem cell.
Mots-clé
Animals Brain/*cytology/*embryology/metabolism Cell Differentiation/*physiology Cell Division/*physiology Cell Lineage/physiology Gene Expression Regulation, Developmental/physiology Humans Nerve Growth Factors/metabolism Neuroglia/cytology/physiology Neurons/*cytology/metabolism Stem Cells/*cytology/metabolism
Pubmed
Web of science
Création de la notice
28/01/2008 13:31
Dernière modification de la notice
03/03/2018 18:17
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