Mammalian neural stem-cell renewal: nature versus nurture
Détails
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Etat: Public
Version: Final published version
Licence: Non spécifiée
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Etat: Public
Version: Final published version
Licence: Non spécifiée
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
ID Serval
serval:BIB_727A94741965
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Mammalian neural stem-cell renewal: nature versus nurture
Périodique
Molecular Neurobiology
ISSN
0893-7648 (Print)
Statut éditorial
Publié
Date de publication
02/2003
Volume
27
Numéro
1
Pages
73-98
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Feb
Research Support, Non-U.S. Gov't
Review --- Old month value: Feb
Résumé
Recent data show that the final events of mammalian brain organogenesis may depend in part on the direct control of neural stem cell (NSC) proliferation and survival. Environmental and intrinsic factors play a role throughout development and during adulthood to regulate NSC proliferation. The NSCs acquire new competences throughout development, including adulthood, and this change in competence is region-specific. The factors controlling NSC survival, undifferentiated state, proliferation, and cell-cycle number are beginning to be identified, but the links between them remain unclear. However, current knowledge should help to formulate an understanding of how a stem cell can generate a new stem cell.
Mots-clé
Animals
Brain/*cytology/*embryology/metabolism
Cell Differentiation/*physiology
Cell Division/*physiology
Cell Lineage/physiology
Gene Expression Regulation, Developmental/physiology
Humans
Nerve Growth Factors/metabolism
Neuroglia/cytology/physiology
Neurons/*cytology/metabolism
Stem Cells/*cytology/metabolism
Pubmed
Web of science
Open Access
Oui
Création de la notice
28/01/2008 12:31
Dernière modification de la notice
14/02/2022 7:55