Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
Details
Serval ID
serval:BIB_69373A259847
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
Journal
Microbes and Infection
ISSN
1286-4579 (Print)
Publication state
Published
Issued date
04/2002
Volume
4
Number
4
Pages
449-60
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Abstract
Macrophage migration inhibitory factor (MIF) is a unique cytokine and critical mediator of host defenses with a role in septic shock and chronic inflammatory and autoimmune diseases. Its mechanism of action is incompletely understood. Here, we attempt to correlate current knowledge on the molecular pathways of MIF activity with its functions in immunity and disease.
Keywords
Animals
Arteriosclerosis/immunology
Arthritis, Rheumatoid/immunology
DNA-Binding Proteins/metabolism
Glomerulonephritis/immunology
Humans
Intracellular Signaling Peptides and Proteins
Lung Diseases/immunology
Macrophage Migration-Inhibitory
Factors/chemistry/genetics/*immunology/physiology
Neoplasms/blood supply/immunology/pathology
Peptide Hydrolases
Receptors, Immunologic/metabolism
Shock, Septic/immunology
Signal Transduction
Transcription Factors/metabolism
Pubmed
Web of science
Create date
25/01/2008 13:35
Last modification date
20/08/2019 14:24
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