Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
Détails
ID Serval
serval:BIB_69373A259847
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease
Périodique
Microbes and Infection
ISSN
1286-4579 (Print)
Statut éditorial
Publié
Date de publication
04/2002
Volume
4
Numéro
4
Pages
449-60
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Résumé
Macrophage migration inhibitory factor (MIF) is a unique cytokine and critical mediator of host defenses with a role in septic shock and chronic inflammatory and autoimmune diseases. Its mechanism of action is incompletely understood. Here, we attempt to correlate current knowledge on the molecular pathways of MIF activity with its functions in immunity and disease.
Mots-clé
Animals
Arteriosclerosis/immunology
Arthritis, Rheumatoid/immunology
DNA-Binding Proteins/metabolism
Glomerulonephritis/immunology
Humans
Intracellular Signaling Peptides and Proteins
Lung Diseases/immunology
Macrophage Migration-Inhibitory
Factors/chemistry/genetics/*immunology/physiology
Neoplasms/blood supply/immunology/pathology
Peptide Hydrolases
Receptors, Immunologic/metabolism
Shock, Septic/immunology
Signal Transduction
Transcription Factors/metabolism
Pubmed
Web of science
Création de la notice
25/01/2008 13:35
Dernière modification de la notice
20/08/2019 14:24
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