Postoperative 3D conformal RT (PORT) in non small cell lung cancer (NSCLC)
Details
Serval ID
serval:BIB_600E08A9B93A
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Abstract (Abstract): shot summary in a article that contain essentials elements presented during a scientific conference, lecture or from a poster.
Collection
Publications
Institution
Title
Postoperative 3D conformal RT (PORT) in non small cell lung cancer (NSCLC)
Title of the conference
11th Annual Meeting of the Scientific Association of Swiss Radiation Oncology (SASRO)
Address
Aarau, Switzerland, March 15-17, 2007
ISSN
0179-7158
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
183
Number
Suppl. 1
Series
Strahlentherapie und Onkologie
Pages
173
Language
english
Abstract
Objective: To assess the outcome of patients treated with involved-field PORT for NSCLC.
Material and Methods: From September 1996 to 2006, data from 75 patients (pts) treated with curative surgery and PORT for
NSCLC were retrospectively analyzed. Median age was 58 years (range, 38-76). There were 5 pts with stage I, 22 with stage II, and 48 with stage III disease. Pneumonectomy or lobectomy was realized in 24 (32%) and 51 (68%) pts, respectively. Adjuvant chemotherapy was given in 15 (20%). All pts had 3D conformal planning.
Median RT dose was 60 Gy, and CTV included bronchial stump and only positive nodal areas.
Results: All pts have completed full treatment. With a median follow-up of 55 months, 26 pts are alive without disease. Median overall survival time was 24 months, with survival rate of 35% at 5 years. The 5-year locoregional control and distant disease-free rates were 80% and 57%, respectively. Pts treated with pneumonectomy and those treated with at least 60-Gy PORT had better outcome. Grade 3 or more CTC v3.0 toxicity was observed only in 4 (5%) pts.
Conclusion: We conclude that involved-field 3D conformal 60-Gy PORT increase significantly locoregional control without increasing lethal toxicity.
Material and Methods: From September 1996 to 2006, data from 75 patients (pts) treated with curative surgery and PORT for
NSCLC were retrospectively analyzed. Median age was 58 years (range, 38-76). There were 5 pts with stage I, 22 with stage II, and 48 with stage III disease. Pneumonectomy or lobectomy was realized in 24 (32%) and 51 (68%) pts, respectively. Adjuvant chemotherapy was given in 15 (20%). All pts had 3D conformal planning.
Median RT dose was 60 Gy, and CTV included bronchial stump and only positive nodal areas.
Results: All pts have completed full treatment. With a median follow-up of 55 months, 26 pts are alive without disease. Median overall survival time was 24 months, with survival rate of 35% at 5 years. The 5-year locoregional control and distant disease-free rates were 80% and 57%, respectively. Pts treated with pneumonectomy and those treated with at least 60-Gy PORT had better outcome. Grade 3 or more CTC v3.0 toxicity was observed only in 4 (5%) pts.
Conclusion: We conclude that involved-field 3D conformal 60-Gy PORT increase significantly locoregional control without increasing lethal toxicity.
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Create date
28/04/2008 11:35
Last modification date
20/08/2019 15:17
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