Preoperative radiation therapy and surgery in the treatment of "bulky" squamous cell carcinoma of the uterine cervix (stage Ib, IIa, and IIb operable tumors)

Details

Serval ID
serval:BIB_543322995F65
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Preoperative radiation therapy and surgery in the treatment of "bulky" squamous cell carcinoma of the uterine cervix (stage Ib, IIa, and IIb operable tumors)
Journal
Radiotherapy and Oncology
Author(s)
Touboul  E., Lefranc  J. P., Blondon  J., Ozsahin  M., Roche  B., Mauban  S., Batel-Copel  L., Schwartz  L. H., Schlienger  M., Laugier  A., Guerin  R. A.
ISSN
0167-8140
Publication state
Published
Issued date
05/1992
Peer-reviewed
Oui
Volume
24
Number
1
Pages
32-40
Notes
Journal Article --- Old month value: May
Abstract
Forty-two women with "bulky" squamous cell carcinoma of the uterine cervix, larger than 5 cm, were treated between 1982 and 1988. The median follow-up was 5 years (from 37 to 106 months). The age range was from 25 to 77 years (mean: 49). There were 14 stage Ib, 5 stage IIa, and 23 stage IIb operable patients. Forty grays were delivered at mid-plane of the pelvis (23 fractions in 31 days) using the four-field technique (6-18 MV). External beam radiation therapy was followed by 20 Gy of intracavitary radiation therapy. Forty-eight days later total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH-BSO) and bilateral pelvic lymphadenectomy were performed. The 3- and 5-year disease-free survival was 83 and 81%, respectively. The 5-year locoregional control rate was 83%. Thirteen patients suffered from mild to severe complications (31%) but there were only two long-term (5%) complications.
Keywords
Brachytherapy Carcinoma, Squamous Cell/mortality/*radiotherapy/*surgery Combined Modality Therapy Female Follow-Up Studies Humans Hysterectomy Lymph Node Excision Middle Aged Ovariectomy Radiotherapy Dosage Radiotherapy, High-Energy Time Factors Uterine Cervical Neoplasms/mortality/*radiotherapy/*surgery
Pubmed
Web of science
Create date
24/01/2008 18:16
Last modification date
20/08/2019 15:09
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