Preoperative radiation therapy and surgery in the treatment of "bulky" squamous cell carcinoma of the uterine cervix (stage Ib, IIa, and IIb operable tumors)

Détails

ID Serval
serval:BIB_543322995F65
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Preoperative radiation therapy and surgery in the treatment of "bulky" squamous cell carcinoma of the uterine cervix (stage Ib, IIa, and IIb operable tumors)
Périodique
Radiotherapy and Oncology
Auteur⸱e⸱s
Touboul  E., Lefranc  J. P., Blondon  J., Ozsahin  M., Roche  B., Mauban  S., Batel-Copel  L., Schwartz  L. H., Schlienger  M., Laugier  A., Guerin  R. A.
ISSN
0167-8140
Statut éditorial
Publié
Date de publication
05/1992
Peer-reviewed
Oui
Volume
24
Numéro
1
Pages
32-40
Notes
Journal Article --- Old month value: May
Résumé
Forty-two women with "bulky" squamous cell carcinoma of the uterine cervix, larger than 5 cm, were treated between 1982 and 1988. The median follow-up was 5 years (from 37 to 106 months). The age range was from 25 to 77 years (mean: 49). There were 14 stage Ib, 5 stage IIa, and 23 stage IIb operable patients. Forty grays were delivered at mid-plane of the pelvis (23 fractions in 31 days) using the four-field technique (6-18 MV). External beam radiation therapy was followed by 20 Gy of intracavitary radiation therapy. Forty-eight days later total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH-BSO) and bilateral pelvic lymphadenectomy were performed. The 3- and 5-year disease-free survival was 83 and 81%, respectively. The 5-year locoregional control rate was 83%. Thirteen patients suffered from mild to severe complications (31%) but there were only two long-term (5%) complications.
Mots-clé
Brachytherapy Carcinoma, Squamous Cell/mortality/*radiotherapy/*surgery Combined Modality Therapy Female Follow-Up Studies Humans Hysterectomy Lymph Node Excision Middle Aged Ovariectomy Radiotherapy Dosage Radiotherapy, High-Energy Time Factors Uterine Cervical Neoplasms/mortality/*radiotherapy/*surgery
Pubmed
Web of science
Création de la notice
24/01/2008 18:16
Dernière modification de la notice
20/08/2019 15:09
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