Rapid detection of Staphylococcus aureus and methicillin resistance in bone and joint infection samples: evaluation of the GeneXpert MRSA/SA SSTI assay.
Details
Serval ID
serval:BIB_4CF45004A2E5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Rapid detection of Staphylococcus aureus and methicillin resistance in bone and joint infection samples: evaluation of the GeneXpert MRSA/SA SSTI assay.
Journal
Diagnostic Microbiology and Infectious Disease
Working group(s)
Lyon Bone Joint Infection Study Group
Contributor(s)
Ferry T., Perpoint T., Boibieux A., Biron F., Ader F., Karsenty J., Daoud F., Lippman J., Braun E., Vallat MP., Miailhes P., Valour F., Chidiac C., Peyramond D., Lustig S., Trouillet F., Neyret P., Guyen O., Vaz G., Lienhart C., Fessy MH., Barrey C., Laurent F., Vandenesch F., Rasigade JP., Morelec I., Deshayes E., Janier M., Giammarile F., Tod M., Gagnieu MC., Goutelle S., Martinez M., Bouaziz A.
ISSN
1879-0070 (Electronic)
ISSN-L
0732-8893
Publication state
Published
Issued date
2014
Volume
78
Number
3
Pages
313-315
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
The GeneXpert MRSA/SA SSTI assay was compared to conventional cultures to detect Staphylococcus aureus and methicillin-resistance from 91 bone and joint infection samples. Sensitivity and specificity were 94.4% and 100%. Three false-positive results were observed, in fact providing from patients known to be infected by S. aureus on the basis of other concomitant osteoarticular samples, which suggests that PCR was more sensitive than culture. This diagnosis accuracy may help shorten toxic and non-optimal empirical therapies such as glycopeptides in case of methicillin-susceptible strains.
Pubmed
Web of science
Create date
26/08/2014 19:37
Last modification date
20/08/2019 15:01
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