Rapid detection of Staphylococcus aureus and methicillin resistance in bone and joint infection samples: evaluation of the GeneXpert MRSA/SA SSTI assay.
Détails
ID Serval
serval:BIB_4CF45004A2E5
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Rapid detection of Staphylococcus aureus and methicillin resistance in bone and joint infection samples: evaluation of the GeneXpert MRSA/SA SSTI assay.
Périodique
Diagnostic Microbiology and Infectious Disease
Collaborateur⸱rice⸱s
Lyon Bone Joint Infection Study Group
Contributeur⸱rice⸱s
Ferry T., Perpoint T., Boibieux A., Biron F., Ader F., Karsenty J., Daoud F., Lippman J., Braun E., Vallat MP., Miailhes P., Valour F., Chidiac C., Peyramond D., Lustig S., Trouillet F., Neyret P., Guyen O., Vaz G., Lienhart C., Fessy MH., Barrey C., Laurent F., Vandenesch F., Rasigade JP., Morelec I., Deshayes E., Janier M., Giammarile F., Tod M., Gagnieu MC., Goutelle S., Martinez M., Bouaziz A.
ISSN
1879-0070 (Electronic)
ISSN-L
0732-8893
Statut éditorial
Publié
Date de publication
2014
Volume
78
Numéro
3
Pages
313-315
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
The GeneXpert MRSA/SA SSTI assay was compared to conventional cultures to detect Staphylococcus aureus and methicillin-resistance from 91 bone and joint infection samples. Sensitivity and specificity were 94.4% and 100%. Three false-positive results were observed, in fact providing from patients known to be infected by S. aureus on the basis of other concomitant osteoarticular samples, which suggests that PCR was more sensitive than culture. This diagnosis accuracy may help shorten toxic and non-optimal empirical therapies such as glycopeptides in case of methicillin-susceptible strains.
Pubmed
Web of science
Création de la notice
26/08/2014 19:37
Dernière modification de la notice
20/08/2019 15:01
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