Accuracy and reliability of noninvasive stroke volume monitoring via ECG-gated 3D electrical impedance tomography in healthy volunteers.

Détails

ID Serval
serval:BIB_42E4363DEFEB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Accuracy and reliability of noninvasive stroke volume monitoring via ECG-gated 3D electrical impedance tomography in healthy volunteers.
Périodique
PloS one
Auteur(s)
Braun F., Proença M., Adler A., Riedel T., Thiran J.P., Solà J.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Statut éditorial
Publié
Date de publication
2018
Peer-reviewed
Oui
Volume
13
Numéro
1
Pages
e0191870
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Résumé
Cardiac output (CO) and stroke volume (SV) are parameters of key clinical interest. Many techniques exist to measure CO and SV, but are either invasive or insufficiently accurate in clinical settings. Electrical impedance tomography (EIT) has been suggested as a noninvasive measure of SV, but inconsistent results have been reported. Our goal is to determine the accuracy and reliability of EIT-based SV measurements, and whether advanced image reconstruction approaches can help to improve the estimates. Data were collected on ten healthy volunteers undergoing postural changes and exercise. To overcome the sensitivity to heart displacement and thorax morphology reported in previous work, we used a 3D EIT configuration with 2 planes of 16 electrodes and subject-specific reconstruction models. Various EIT-derived SV estimates were compared to reference measurements derived from the oxygen uptake. Results revealed a dramatic impact of posture on the EIT images. Therefore, the analysis was restricted to measurements in supine position under controlled conditions (low noise and stable heart and lung regions). In these measurements, amplitudes of impedance changes in the heart and lung regions could successfully be derived from EIT using ECG gating. However, despite a subject-specific calibration the heart-related estimates showed an error of 0.0 ± 15.2 mL for absolute SV estimation. For trending of relative SV changes, a concordance rate of 80.9% and an angular error of -1.0 ± 23.0° were obtained. These performances are insufficient for most clinical uses. Similar conclusions were derived from lung-related estimates. Our findings indicate that the key difficulty in EIT-based SV monitoring is that purely amplitude-based features are strongly influenced by other factors (such as posture, electrode contact impedance and lung or heart conductivity). All the data of the present study are made publicly available for further investigations.

Mots-clé
Adult, Algorithms, Calibration, Electric Impedance, Electrocardiography/statistics & numerical data, Exercise/physiology, Female, Healthy Volunteers, Humans, Image Interpretation, Computer-Assisted, Image Processing, Computer-Assisted/statistics & numerical data, Imaging, Three-Dimensional/statistics & numerical data, Male, Posture/physiology, Reproducibility of Results, Stroke Volume/physiology, Tomography/instrumentation, Tomography/methods, Tomography/statistics & numerical data
Pubmed
Web of science
Open Access
Oui
Création de la notice
01/02/2018 20:37
Dernière modification de la notice
08/05/2019 17:45
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