Chronic myelomonocytic leukemia in the light of the WHO proposals.

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Serval ID
serval:BIB_4001811B48FA
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Production externe
Title
Chronic myelomonocytic leukemia in the light of the WHO proposals.
Journal
Haematologica
Author(s)
Germing U., Strupp C., Knipp S., Kuendgen A., Giagounidis A., Hildebrandt B., Aul C., Haas R., Gattermann N., Bennett J.M.
ISSN
1592-8721 (Electronic)
ISSN-L
0390-6078
Publication state
Published
Issued date
07/2007
Peer-reviewed
Oui
Volume
92
Number
7
Pages
974-977
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The WHO classification moved CMML to myeloproliferative/myelodysplastic disorders, and defined CMML I and CMML II according to medullary and peripheral blast count. To confirm these proposals, we analyzed 266 patients with CMML I and 73 patients with CMML II. Median survival time was 20 months for CMML I, and 15 months for CMML II (p<0.005). The cumulative risk of AML evolution differed between patient groups (p=0,001). No conclusive differences in clinical, morphologic, hematologic or cytogenetic parameters were found. These data support the WHO proposals for the classifi-cation of CMML.
Keywords
Classification, Humans, Leukemia, Myelomonocytic, Chronic/classification, Myeloproliferative Disorders/classification, World Health Organization
DOI
10.3324/haematol.11051
Pubmed
17606449
Web of science
000247703300016
Open Access
Yes
Create date
16/07/2019 13:11
Last modification date
21/08/2019 6:36
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