Chronic myelomonocytic leukemia in the light of the WHO proposals.

Détails

ID Serval
serval:BIB_4001811B48FA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Chronic myelomonocytic leukemia in the light of the WHO proposals.
Périodique
Haematologica
Auteur⸱e⸱s
Germing U., Strupp C., Knipp S., Kuendgen A., Giagounidis A., Hildebrandt B., Aul C., Haas R., Gattermann N., Bennett J.M.
ISSN
1592-8721 (Electronic)
ISSN-L
0390-6078
Statut éditorial
Publié
Date de publication
07/2007
Peer-reviewed
Oui
Volume
92
Numéro
7
Pages
974-977
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
The WHO classification moved CMML to myeloproliferative/myelodysplastic disorders, and defined CMML I and CMML II according to medullary and peripheral blast count. To confirm these proposals, we analyzed 266 patients with CMML I and 73 patients with CMML II. Median survival time was 20 months for CMML I, and 15 months for CMML II (p<0.005). The cumulative risk of AML evolution differed between patient groups (p=0,001). No conclusive differences in clinical, morphologic, hematologic or cytogenetic parameters were found. These data support the WHO proposals for the classifi-cation of CMML.
Mots-clé
Classification, Humans, Leukemia, Myelomonocytic, Chronic/classification, Myeloproliferative Disorders/classification, World Health Organization
Pubmed
Web of science
Open Access
Oui
Création de la notice
16/07/2019 12:11
Dernière modification de la notice
21/08/2019 5:36
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