Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.

Détails

ID Serval
serval:BIB_3C81678B0325
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Reassessment of recommended imipenem doses in febrile neutropenic patients with hematological malignancies.
Périodique
Antimicrobial Agents and Chemotherapy
Auteur(s)
Lamoth F., Buclin T., Csajka C., Pascual A., Calandra T., Marchetti O.
ISSN
1098-6596
Statut éditorial
Publié
Date de publication
2009
Peer-reviewed
Oui
Volume
53
Numéro
2
Pages
785-787
Langue
anglais
Résumé
Imipenem plasma concentrations were analyzed in 57 febrile neutropenic patients using the NONMEM program. The recommended 2-g/day regimen achieved coverage of the most common bacteria (MIC(90) = 1 mg/liter) during the whole dosing interval in only 53% of patients. This goal was achieved in 90% of patients with 3 g/day.
Pubmed
Web of science
Open Access
Oui
Création de la notice
26/02/2009 16:28
Dernière modification de la notice
20/08/2019 13:32
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